PERBEDAAN PENGARUH PAPARAN MUSIK MOZART, BEETHOVEN, DAN CHOPIN SELAMA KEBUNTINGAN TERHADAP INDEKS APOPTOSIS SEL NEURON DI CEREBELLUM Rattus norvegicus BARU LAHIR

Abstract

The efforts that can be done to improve
brain cells in the prenatal period is the provision of
nutrients and good stimulation. Exposure to classical
music such as Mozart, Beethoven, and Chopin
music can increase the wave of brain activity. During
pregnancy, Mozart music is proven to decrease the
apoptosis of neuronal.
Analyzing the difference of apoptosis
neuronal of cerebrum and cerebellum of newborn
baby of Rattus norvegicus that are exposed to the
Mozart, Beethoven, and Chopin music, and that is
not exposed to music during pregnancy.
Laboratory experimental research, posttestonly control group design. Subjects were female
pregnant Rattus norvegicus, grouped into 4 random
groups: 1 control group and 3 treatments groups;
with 6 samples each. Subjects were super ovulated,
and 65 dB intensity of music is played for an hour at
20.00-21.00 on the subjects on 10th day of
pregnancy. On 20th day of pregnancy, the mothers
was dissected using SC technique. 2 heaviest
newborn babies of Rattus norvegicus were taken.
Statistical test concluded there was
significant differences of apoptosis neuronal of
cerebellum of newborn babies of Rattus norvegicus
among the exposure to Mozart, Beethoven, and
Chopin music, and without the exposure to music
with value of p=0,033 in cerebellum.
In conclution, the exposure of Mozart’s
music during pregnancy perform expression of
BDNF cerebellum in the offspring-rat was higher
than exposed Beethoven’s music, Chopin and not
exposed to music.