Model perawatan untuk penderita penyakit ginjal kronis: Sistematika Review
Keywords:
Chronic kidney disease, care model, systematic observation
Abstract
Chronic kidney disease (CKD) is a common disease and places an increasing burden on patients and health services. However, the optimal treatment model for patients with CKD remains unclear. We systematically reviewed the clinical effectiveness of different care models for the management of CKD. A comprehensive search of eight data bases was conducted for articles published from 1992 to 2024. We included randomized controlled trials assessing any model of care in the management of adults with pre-dialysis CKD, reporting renal, cardiovascular, mortality and other results. Data extraction and quality assessment were performed independently by two authors. The results are summarized narratively. Nine articles (seven studies) were included. Four models of care were identified: nurse-led, multidisciplinary specialist team, pharmacist-led, and self-management. Nurse-led and pharmacist-led care reported increased rates of prescribing of medications relevant to CKD. High heterogeneity between studies and across studies carries a high risk of bias. Nurse-led care and multidisciplinary specialist care were associated with small improvements in blood pressure control. Evidence of long-term improvements in renal, cardiovascular or mortality endpoints is limited by short follow-up.
References
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Beaulieu, Monica, and Adeera Levin. 2009. “Analysis of Multidisciplinary Care Models and Interface With Primary Care in Management of Chronic Kidney Disease.” Seminars in Nephrology 29(5):467–74. doi: https://doi.org/10.1016/j.semnephrol.2009.06.003.
Canaud, Bernard, Andrew Davenport, Hélène Leray-Moragues, Marion Morena-Carrere, Jean Paul Cristol, Jeroen Kooman, and Peter Kotanko. 2024. “Digital Health Support: Current Status and Future Development for Enhancing Dialysis Patient Care and Empowering Patients.” Toxins 16(5). doi: 10.3390/toxins16050211.
Chan, Juliana C., Wing-Yee So, Chun-Yip Yeung, Gary T. Ko, Ip-Tim Lau, Man-Wo Tsang, Kam-Piu Lau, Sing-Chung Siu, June K. Li, and Vincent T. Yeung. 2009. “Effects of Structured versus Usual Care on Renal Endpoint in Type 2 Diabetes: The SURE Study: A Randomized Multicenter Translational Study.” Diabetes Care 32(6):977–82.
Chen, Sue-Hsien, Yun-Fang Tsai, Chiao-Yin Sun, I. Wen Wu, Chin-Chan Lee, and Mai-Szu Wu. 2011. “The Impact of Self-Management Support on the Progression of Chronic Kidney Disease—a Prospective Randomized Controlled Trial.” Nephrology Dialysis Transplantation 26(11):3560–66.
Chesnaye, Nicholas C., Alberto Ortiz, Carmine Zoccali, Vianda S. Stel, and Kitty J. Jager. 2024. “The Impact of Population Ageing on the Burden of Chronic Kidney Disease.” Nature Reviews Nephrology 20(9):569–85. doi: 10.1038/s41581-024-00863-9.
Cockwell, Paul, and Lori-Ann Fisher. 2020. “The Global Burden of Chronic Kidney Disease.” The Lancet 395(10225):662–64. doi: 10.1016/S0140-6736(19)32977-0.
Cooney, Danielle, Helen Moon, Yang Liu, Richard Tyler Miller, Adam Perzynski, Brook Watts, and Paul E. Drawz. 2015. “A Pharmacist Based Intervention to Improve the Care of Patients with CKD: A Pragmatic, Randomized, Controlled Trial.” BMC Nephrology 16:1–9.
Devins, Gerald M., David C. Mendelssohn, Paul E. Barré, and Yitzchak M. Binik. 2003. “Predialysis Psychoeducational Intervention and Coping Styles Influence Time to Dialysis in Chronic Kidney Disease.” American Journal of Kidney Diseases 42(4):693–703.
Elshahat, Sarah, Paul Cockwell, Alexander P. Maxwell, Matthew Griffin, Timothy O’Brien, and Ciaran O’Neill. 2020. “The Impact of Chronic Kidney Disease on Developed Countries from a Health Economics Perspective: A Systematic Scoping Review.” PLOS ONE 15(3):e0230512-.
Hall, John E., Jussara M. do Carmo, Alexandre A. da Silva, Zhen Wang, and Michael E. Hall. 2019. “Obesity, Kidney Dysfunction and Hypertension: Mechanistic Links.” Nature Reviews Nephrology 15(6):367–85. doi: 10.1038/s41581-019-0145-4.
Harris, LisaE, FriedrichC Luft, DavidW Rudy, JosephG Kesterson, and WilliamM Tierney. 1998. “Effects of Multidisciplinary Case Management in Patients with Chronic Renal Insufficiency.” The American Journal of Medicine 105(6):464–71.
Hermes, Sebastian, Tobias Riasanow, Eric K. Clemons, Markus Böhm, and Helmut Krcmar. 2020. “The Digital Transformation of the Healthcare Industry: Exploring the Rise of Emerging Platform Ecosystems and Their Influence on the Role of Patients.” Business Research 13(3):1033–69.
Koraishy, Farrukh M., and Rajeev Rohatgi. 2020. “Telenephrology: An Emerging Platform for Delivering Renal Health Care.” American Journal of Kidney Diseases 76(3):417–26. doi: https://doi.org/10.1053/j.ajkd.2020.02.442.
Kovesdy, Csaba P. 2022. “Epidemiology of Chronic Kidney Disease: An Update 2022.” Kidney International Supplements 12(1):7–11. doi: https://doi.org/10.1016/j.kisu.2021.11.003.
Kumar, Mahendra, Shah Dev, Muhammad Usman Khalid, Sowmya Manjari Siddenthi, Muhammad Noman, Chris John, Chiderah Akubuiro, Anum Haider, Riya Rani, Maham Kashif, Giustino Varrassi, Mahima Khatri, Satesh Kumar, and Tamam Mohamad. 2023. “The Bidirectional Link Between Diabetes and Kidney Disease: Mechanisms and Management.” Cureus. doi: 10.7759/cureus.45615.
Lameire, Norbert H., Adeera Levin, John A. Kellum, Michael Cheung, Michel Jadoul, Wolfgang C. Winkelmayer, Paul E. Stevens, Fergus J. Caskey, Chris K. T. Farmer, Alejandro Ferreiro Fuentes, Masafumi Fukagawa, Stuart L. Goldstein, Grace Igiraneza, Andreas Kribben, Edgar V Lerma, Andrew S. Levey, Kathleen D. Liu, Jolanta Małyszko, Marlies Ostermann, Neesh Pannu, Claudio Ronco, Simon Sawhney, Andrew D. Shaw, and Nattachai Srisawat. 2021. “Harmonizing Acute and Chronic Kidney Disease Definition and Classification: Report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference.” Kidney International 100(3):516–26. doi: https://doi.org/10.1016/j.kint.2021.06.028.
Luckett, Tim, Marcus Sellars, Jennifer Tieman, Carol A. Pollock, William Silvester, Phyllis N. Butow, Karen M. Detering, Frank Brennan, and Josephine M. Clayton. 2014. “Advance Care Planning for Adults With CKD: A Systematic Integrative Review.” American Journal of Kidney Diseases 63(5):761–70. doi: https://doi.org/10.1053/j.ajkd.2013.12.007.
Page, Matthew J., Joanne E. McKenzie, Patrick M. Bossuyt, Isabelle Boutron, Tammy C. Hoffmann, Cynthia D. Mulrow, Larissa Shamseer, Jennifer M. Tetzlaff, Elie A. Akl, Sue E. Brennan, Roger Chou, Julie Glanville, Jeremy M. Grimshaw, Asbjørn Hróbjartsson, Manoj M. Lalu, Tianjing Li, Elizabeth W. Loder, Evan Mayo-Wilson, Steve McDonald, Luke A. McGuinness, Lesley A. Stewart, James Thomas, Andrea C. Tricco, Vivian A. Welch, Penny Whiting, and David Moher. 2021. “The PRISMA 2020 Statement: An Updated Guideline for Reporting Systematic Reviews.” BMJ 372:n71. doi: 10.1136/bmj.n71.
Peeters, Mieke J., Arjan D. van Zuilen, Jan A. J. G. van den Brand, Michiel L. Bots, Marjolijn van Buren, Marc A. G. J. Ten Dam, Karin A. H. Kaasjager, Gerry Ligtenberg, Yvo W. J. Sijpkens, and Henk E. Sluiter. 2014. “Nurse Practitioner Care Improves Renal Outcome in Patients with CKD.” Journal of the American Society of Nephrology 25(2):390–98.
Rivera, Eleanor, Maya N. Clark-Cutaia, Sarah J. Schrauben, Raymond R. Townsend, James P. Lash, Mary Hannan, Bernard G. Jaar, Hernan Rincon-Choles, Sheru Kansal, Jiang He, Jing Chen, and Karen B. Hirschman. 2022. “Treatment Adherence in CKD and Support From Health Care Providers: A Qualitative Study.” Kidney Medicine 4(11):100545. doi: https://doi.org/10.1016/j.xkme.2022.100545.
Ruiz-Ortega, Marta, Sandra Rayego-Mateos, Santiago Lamas, Alberto Ortiz, and Raul R. Rodrigues-Diez. 2020. “Targeting the Progression of Chronic Kidney Disease.” Nature Reviews Nephrology 16(5):269–88. doi: 10.1038/s41581-019-0248-y.
Salgado, Teresa M., Cassyano J. Correr, Rebekah Moles, Shalom I. Benrimoj, and Fernando Fernandez-Llimos. 2013. “Assessing the Implementability of Clinical Pharmacist Interventions in Patients with Chronic Kidney Disease: An Analysis of Systematic Reviews.” Annals of Pharmacotherapy 47(11):1498–1506.
Scherpbier-de Haan, Nynke D., Gerald M. M. Vervoort, Chris van Weel, Jozé C. C. Braspenning, Jan Mulder, Jack F. M. Wetzels, and Wim J. C. De Grauw. 2013. “Effect of Shared Care on Blood Pressure in Patients with Chronic Kidney Disease: A Cluster Randomised Controlled Trial.” British Journal of General Practice 63(617):e798–806.
Skivington, Kathryn, Lynsay Matthews, Sharon Anne Simpson, Peter Craig, Janis Baird, Jane M. Blazeby, Kathleen Anne Boyd, Neil Craig, David P. French, and Emma McIntosh. 2021. “A New Framework for Developing and Evaluating Complex Interventions: Update of Medical Research Council Guidance.” Bmj 374.
Strand, Haakan, and Deborah Parker. 2012. “Effects of Multidisciplinary Models of Care for Adult Pre-Dialysis Patients with Chronic Kidney Disease: A Systematic Review.” JBI Evidence Implementation 10(1):53–59.
Suchitra Pal, Santhna Letchmi Panduragan, and Faridah Mohd Said. 2024. “Recent Trend in the Care of Chronic Kidney Disease Patients: A Shift from Paternalistic to Collaborative Approach.” Asian Journal of Medical Sciences 15(10):192–99. doi: 10.3126/ajms.v15i10.68675.
Wouters, Olivier J., Donal J. O’Donoghue, James Ritchie, Panos G. Kanavos, and Andrew S. Narva. 2015. “Early Chronic Kidney Disease: Diagnosis, Management and Models of Care.” Nature Reviews Nephrology 11(8):491–502. doi: 10.1038/nrneph.2015.85.
Yan, Ming Tso, Chia Ter Chao, and Shih Hua Lin. 2021. “Chronic Kidney Disease: Strategies to Retard Progression.” International Journal of Molecular Sciences 22(18).
Van Zuilen, A. D., P. J. Blankestijn, Marjolijn van Buren, M. A. Ten Dam, K. A. Kaasjager, Gerry Ligtenberg, Y. W. Sijpkens, H. E. Sluiter, P. J. van de Ven, and Gerald Vervoort. 2011. “Nurse Practitioners Improve Quality of Care in Chronic Kidney Disease: Two-Year Results of a Randomised Study.” Neth J Med 69(11):517–26.
Van Zuilen, Arjan D., Michiel L. Bots, Arzu Dulger, Ingeborg Van Der Tweel, Marjolijn Van Buren, Marc A. G. J. Ten Dam, Karin A. H. Kaasjager, Gerry Ligtenberg, Yvo W. J. Sijpkens, and Henk E. Sluiter. 2012. “Multifactorial Intervention with Nurse Practitioners Does Not Change Cardiovascular Outcomes in Patients with Chronic Kidney Disease.” Kidney International 82(6):710–17.
