Perbedaan Pengaruh Paparan Musik Mozart, Beethoven dan Chopin Selama Kebuntingan Terhadap Ekspresi Brain Derived Neurotrophic Factor Di Crebellum Rattus norvegicus Baru Lahir

Abstract

Indonesia's Human Development Index
(HDI) for 2015 was ranked 113 out of 188 countries.
Education would be needed to raise HDI’s rank. One
principle component of education is the quality of the
brain. BDNF expression in the brain was affected by
many stimuli. Mozart classical music had a
neurobiological effect which had ability to increase
BDNF. Whereas, other classical musics such as
Beethoven and Chopin had never been studied. This
study aims to cerebellum’s BDNF expression in the
offspring of Rattus norvegicus that ere exposed to
the Mozart , Beethoven, Chopin during pregnancy.
The method used is pure laboratory
experiment with posttest only control group design.
The variables measured were BDNF expression in
the brain. The samples were divided into 4 groups of
each 6 rats.
The results showed that significant
differences in BDNF expressions between control
group and Mozart (p=0,023; p<0,05), between
Mozart group and Chopin (p=0,003). There were no
statistically detected differences between control
group and Beethoven (p=0,256), control group and
Chopin (p=0,684), Mozart group and Beethoven
(p=0,092) and Beethoven group and Chopin
(p=0,292). Based on the above results it can be
concluded that the exposure of Mozart’s music
during pregnancy had a higher expression of BDNF
in the offspring-rat’s cerebellum compare to those
which exposed by Beethoven and Chopin’s music.